| 产品编号 |
bs-42066P |
| 英文名称 |
Recombinant human PALB2 protein
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| 中文名称 |
重组人乳腺癌易感基因相关蛋白2 |
| 别 名 |
DKFZp667I166; 4732427B05; BC066140; DKFZp686E1054; FANCN; FANCN GENE; FLJ21816; OTTMUSP00000025884; PALB2; partner and localizer of BRCA2; RGD1304759; PALB2_HUMAN. |
| 克 隆 号 |
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| 理论分子量 |
38 kDa |
| 检测分子量 |
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| 性 状 |
Lyophilized or Liquid |
| 浓 度 |
>0.5mg/ml |
| 物 种 |
Human |
| 序 列 |
841-1186/1186 |
| 纯 度 |
> 90% as determined by SDS-PAGE method |
| 纯化方法 |
AC |
| 表达系统 |
E.coli |
| 活性 |
Not tested |
| 标签 |
His&Trx&S |
| 缓 冲 液 |
20 mM Tris-Hcl(pH=9.0). |
| 保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. Essential partner of BRCA2 that promotes the localization and stability of BRCA2. Also enables its recombinational repair and checkpoint functions of BRCA2. May act by promoting stable association of BRCA2 with nuclear structures, allowing BRCA2 to escape the effects of proteosome-mediated degradation.
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| 产品图片 |
The purity of the protein is greater than 80% as determined by reducing SDS-PAGE.
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