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Rabbit Anti-TNFRSF12A/CD266  antibody (bsm-52646R)
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说明书: 50ul  100ul  
50ul/1580.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-52646R
英文名称 TNFRSF12A/CD266
中文名称 肿瘤坏死因子配体超家族成员12A(CD266)重组兔单抗
别    名 CD 266; CD266; CD266 antigen; TWEAKR; FGF inducible 14; FGF-inducible 14; Fibroblast growth factor inducible immediate early response protein 14; Fibroblast growth factor-inducible immediate-early response protein 14; FN 14; FN14; TNFRSF 12A; TNR12_HUMAN; Tumor necrosis factor receptor superfamily member 12A; TWEAK R; Tweak receptor; Tweak-receptor; TweakR; Type I transmembrane protein Fn 14; Type I transmembrane protein Fn14.  
研究领域 肿瘤  心血管  细胞生物  免疫学  信号转导  生长因子和激素  细胞膜受体  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 2C14
交叉反应 (predicted: Human,Mouse,Rat)
产品应用 WB=1:300-5000, IHC-P=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 11kDa
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TWEAKR 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 TWEAK (otherwise known as TNFRSF12A, Tumor necrosis factor receptor superfamily member 12A), is a member of the TNF family and was first described as a weak inducer of apoptosis in some cell types. It is thought to promote angiogenesis and the proliferation of endothelial cells as well as modulating cellular adhesion to matrix proteins. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library.
Function : Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.

SWISS:
Q9NP84

Gene ID:
51330

Database links:

Entrez Gene: 51330 Human

Entrez Gene: 27279 Mouse

Entrez Gene: 302965 Rat

SwissProt: Q9NP84 Human

SwissProt: Q9CR75 Mouse



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