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MouseAnti-Cystatin-C  antibody (V0505)
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说明书: 100ug  
100ug/1880.00元
大包装/询价
产品编号 V0505
英文名称 Cystatin-C
中文名称 胱抑素C单克隆抗体
别    名 Cystatin-3; Cystatin3; Cystatin 3; CystatinC; CST 3; CST3; CST-3; Cystatin C; AD 8; AD8; Amyloid angiopathy and cerebral hemorrhage; Cst 3; Cst3; CST3 protein; Gamma trace; HCCAA; Neuroendocrine basic polypeptide; Post gamma globulin; ARMD11; MGC117328; CYSC; CYTC_HUMAN.  
研究领域 肿瘤  心血管  细胞生物  免疫学  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 1C5
交叉反应 (predicted: Human, )
产品应用 ICA= 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 13kDa
细胞定位 分泌型蛋白 
性    状 Liquid
免 疫 原 Recombinant Human Cys-C Protein: 27-146/146 
亚    型 IgG1
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M PBS(pH7.4)
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin, or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.

SWISS:
P01034

Gene ID:
1471

应用推荐(Capture-Detection):1C3&1C5-6C1

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