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Rabbit Anti-ROR1  antibody (bs-34232R)
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说明书: 50ul  100ul  
50ul/1180.00元
100ul/1980.00元
大包装/询价
产品编号 bs-34232R
英文名称 ROR1
中文名称 非酪氨酸蛋白激酶跨膜受体ROR1抗体
别    名 ROR1_HUMAN; ROR1_MOUSE; Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1; NTRKR1; receptor tyrosine kinase like orphan receptor 1; dJ537F10.1;   
研究领域 染色质和核信号  神经生物学  信号转导  激酶和磷酸酶  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse)
产品应用 WB=1:300-800
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 100kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse ROR1 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm.

SWISS:
Q9Z139

Gene ID:
26563

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