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Rabbit Anti-Bak / Biotin antibody (bs-22928R-Bio)
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说明书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-22928R-Bio
英文名称 Bak / Biotin
中文名称 生物素标记的Bcl-2同源拮抗剂抗体
别    名 Apoptosis Regulator Bak; BAK 1; BAK; BAK like; Bak NT; BAK1; Bcl 2 homologous antagonist/killer; Bcl 2 like 7 protein; Bcl2 homologous antagonist killer; Bcl2 like 7 Protein; BCL2-antagonist/killer 1; BCL2L7; CDN 1; CDN1; Cell death inhibitor 1; MGC117255; MGC3887; NBak; Pro apoptotic protein BAK; BAK_HUMAN; BAK_MOUSE;   
研究领域 免疫学  细胞凋亡  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 23kDa
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Bak: 71-171/211 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]

SWISS:
O08734

Gene ID:
578

Database links:
Entrez Gene: 578 Human
Entrez Gene: 12018 Mouse
Omim: 600516 Human
SwissProt: Q16611 Human
SwissProt: Q6I9T6 Human
SwissProt: O08734 Mouse
Unigene: 485139 Human
Unigene: 2443 Mouse


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