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GBP2 Rabbit pAb (bs-25622R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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产品编号 bs-25622R
英文名称 GBP2 Rabbit pAb
中文名称 G蛋白结合蛋白2抗体
别    名 GBP 2; GBP2; GBP-2; GTP binding protein 2; Guanine nucleotide binding protein 2; Guanylate binding protein 2 interferon inducible; HuGBP 2; HuGBP2; GBP2_HUMAN.  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human (predicted: Rabbit,Pig,Cow,Horse)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 67 kDa
检测分子量
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GBP2: 51-150/591 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013]

Function:
Guanylate-binding proteins (GBPs) are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). GBP2 is a GTPase that converts GTP to GDP and GMP.

Subunit:
Homodimerizes upon GTP-binding, dimerization is required for the second hydrolysis step from GDP to GMP. Can also heterodimerize with other members of the family.

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side

Similarity:
Belongs to the GBP family.

SWISS:
P32456

Gene ID:
2634

Database links:

Entrez Gene: 2634 Human

Entrez Gene: 14469 Mouse

Entrez Gene: 171164 Rat

Omim: 600412 Human

SwissProt: P32456 Human

SwissProt: Q9Z0E6 Mouse

SwissProt: Q63663 Rat



产品图片
Sample: Lane 1: Human A549 cell lysates Lane 2: Human K562 cell lysates Primary: Anti-GBP2 (bs-25622R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 67 kDa Observed band size: 67 kDa
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