| 产品编号 | bs-42060P |
| 英文名称 | Recombinant human Fibulin 5 protein, C-His |
| 中文名称 | 重组人衰老关键蛋白 |
| 别 名 | ARMD3; Dance; Developmental arteries and neural crest EGF like protein; FBLN5; FIBL 5; Developmental arteries and neural crest EGF-like protein; EVEC; Fbln5; FBLN5_HUMAN; UP50; FIBL 5; FIBL-5; Fibulin-5; FLJ90059; Urine p50 protein. |
| 理论分子量 | 30kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | >0.5mg/ml |
| 纯 度 | >90% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | E.coli |
| 标签 | c-His |
| 缓 冲 液 | 20mM Tris-Hcl (pH=8.0) with 8M Urea, 5mM DTT |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Fibulin 5: A protein that belongs to a family of extracellular proteins expressed in the basement membranes of blood vessels. Fibulin 5 may be essential for the polymerization of elastin. Missense mutations in FBLN5, the gene that encodes fibulin 5, appear responsible for 1-2% of cases of age-related macular degeneration (AMD). FBLN5 is located on chromosome 14 in band 14q32.1. See also: Fibulin 3. May play a role in vascular growth and maturation during development and in lesions of injured vessels. SWISS: Q9UBX5 Gene ID: 10516 Fibulin-5 Fibulin-5亦称为FBLN-5、DANCE或EVEC是细胞外基质蛋白质家族的一员，在组织器官发育、重塑和修复过程中起重要作用，并与内皮细胞相互作用.Fibulin-5广泛分布于富含弹性蛋白的组织, 能直接与原弹性蛋白结合,并将后者锚于细胞表面,这对形成弹性纤维十分关键, 对血管的发育和修复具有重要作用.此外,Fibuljn-5还能促进创口愈合, 与细胞的增殖、运动和侵袭有关 fibulin-5有学者称“皮肤衰老关键蛋白”与皮肤弹性有关的蛋白，对于起着固定细胞外壁、保持肌肤紧绷、维护肺部和血管柔韧性作用的弹性纤维的发育十分关键. 还有学者认为：fibulin-5能够抑制血管的形成，该蛋白质在肿瘤转移过程中表达降低或消失，将有可能用于肿瘤治疗方面的研究。 |
| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
