产品编号 |
bs-43590P |
英文名称 |
Recombinant mouse CD86 protein, C-His (HEK293)
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中文名称 |
重组小鼠CD86蛋白 |
别 名 |
CD28LG2; FUN1; LAB72; Activation B7 2 antigen; Activation B7-2 antigen 3; CD86_HUMAN; Activation B7-2 antigen; Activation B72 antigen; B lymphocyte activation antigen B7 2; B lymphocyte activation antigen B72; B-lymphocyte activation antigen B7-2 2; B-lymphocyte activation antigen B7-2; B7 2; B7 2 antigen; B7; B7-2; B7.2; B70; B72 antigen; BU63; CD 86; CD28 antigen ligand 2 2; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2; CD86 antigen; CD86 molecule; CLS1; CTLA 4 counter receptor B7 2; CTLA 4 counter receptor B7.2; CTLA-4 counter-receptor B7.2 2, 3; CTLA4 counter receptor B72; Early T-cell costimulatory molecule 1; ETC-1; FUN 1; LAB72; Ly-58; Ly58; MB7; MB7-2; Membrane glycoprotein; MGC34413; T lymphocyte activation antigen CD86; T-lymphocyte activation antigen CD86; TS/A-2. |
克 隆 号 |
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理论分子量 |
26.3 kDa |
检测分子量 |
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性 状 |
Lyophilized or Liquid |
浓 度 |
>0.5mg/ml |
物 种 |
Mouse |
纯 度 |
>90% as determined by SDS-PAGE |
纯化方法 |
AC |
内毒素 |
Not tested |
表达系统 |
HEK293 cell |
标签 |
C-His |
缓 冲 液 |
PBS (pH7.4). |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].
CD86是一个很重要要的辅助刺激分子,CD86作为CD28的辅助刺激分子,提供 T 细胞活化的辅助信号,它们之间的结合和随后介导的信号转导是 T 细胞和 APC 相互协作的重要分子基础。
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产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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