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产品中心-北京博奥森生物技术有限公司
Recombinant human ROBO4 protein, C-His (HEK293) (bs-43625P)
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说明书: 100ug  500ug  
100ug/4800.00元
500ug/15000.00元
大包装/询价

产品编号 bs-43625P
英文名称 Recombinant human ROBO4 protein, C-His (HEK293)
中文名称 重组人肿瘤血管内皮调节蛋白Robo4
别    名 Magic roundabout; MRB; Robo 4; Roundabout homolog 4; Roundabout homolog 4 magic roundabout; Roundabout homolog 4 Precursor; ROBO4_HUMAN.  
理论分子量 48.6kDa
性    状 Lyophilized or Liquid
浓    度 >0.5mg/ml
物    种 Human
序    列 28-467/1007
纯    度 >90% as determined by SDS-PAGE
纯化方法 AC
内毒素 Not analyzed
表达系统 HEK293 cell
标签 C-His
缓 冲 液 PBS (pH=7.4)
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Robo4 is a vascular specific receptor that is a repulsive cue to migrating endothelial cells during vascular development. Guidance and patterning of axons are orchestrated by cell surface receptors and ligands that provide directional cues. Interactions between the Robo receptor and Slit ligand families of proteins initiate signaling cascades that repel axonal outgrowth. In contrast to known neuronal Robo family members, the arrangement of the extracellular domains of Robo4 diverges significantly from that of all other Robo family members. Robo4 is specifically expressed in the vascular endothelium during murine embryonic development; the only Robo family member expressed in primary endothelial cells. Robo4 also has a role in regulating the migration of endothelial cells during tumor angiogenesis.

SWISS:
Q8WZ75

Gene ID:
54538

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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