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Recombinant human Glypican 3 protein, C-His (GEK293) (bs-43636P)
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说明书: 100ug  500ug  
100ug/4800.00元
500ug/15000.00元
大包装/询价
产品编号 bs-43636P
英文名称 Recombinant human Glypican 3 protein, C-His (GEK293)
中文名称 重组人磷脂酰基醇蛋白聚糖-3
别    名 GPC3; glypican3; glypican-3; Intestinal protein OCI-5; GTR2-2; MXR7.Intestinal protein OCI-5; GPC3_HUMAN.  
理论分子量 62.2kDa
性    状 Lyophilized or Liquid
浓    度 >0.5mg/ml
物    种 Human
序    列 25-559/580
纯    度 >90% as determined by SDS-PAGE
纯化方法 AC
内毒素 Not analyzed
表达系统 HEK293 cell
标签 C-His
缓 冲 液 PBS (pH=7.4)
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

SWISS:
P51654

Gene ID:
2719

GPC-3磷脂酰基醇蛋白聚糖-3是一种硫酸类肝素蛋白多糖,GPC-3在不同的组织中具有不同的生物学功能,甚至起着完全不同的作用,可能与肿瘤组织类型、发病机制等密切相关.GPC3在绝大多数HCC(肝细胞癌)患者有表达。
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