产品编号 | bs-42194P |
英文名称 | Recombinant human OST-beta protein, N-GST |
中文名称 | 重组人有机溶质转运蛋白OSTβ蛋白 |
别 名 | organic solute transporter beta (Ostbeta); Organic solute transporter subunit beta; Ostbeta; Ost beta; OSTB; OSTB_HUMAN. |
理论分子量 | 35.5kDa |
性 状 | Liquid |
浓 度 | >1mg/ml |
物 种 | Human |
序 列 | 57-128/128 |
纯 度 | >90% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | Not analyzed |
表达系统 | E.coli |
标签 | N-GST |
缓 冲 液 | PBS (pH=7.4) with 15mM GSH |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine, liver, testis, kidney and adrenal gland. OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor). This genetic regulation suggests that in response to changes in intracellular bile acid levels, bile acids adjust the rate of their own efflux from enterocytes. OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane. Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus. Though widely expressed, OST Beta is present at highest levels in ileum. SWISS: Q86UW2 Gene ID: 123264 |
产品图片 | |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |