| 产品编号 |
bs-47604P |
| 英文名称 |
Recombinant human ITGA2B Protein, C-His
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| 中文名称 |
重组人 ITGA2B 蛋白 |
| 别 名 |
GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD antigen CD41 |
| 克 隆 号 |
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| 理论分子量 |
10.5 kDa |
| 检测分子量 |
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| 性 状 |
Liquid |
| 序 列 |
Gln751-Asn820 |
| 表达系统 |
E.coli |
| 缓 冲 液 |
150 mM PBS(pH 7.4) |
| 保存条件 |
Stored at -70℃ or -20℃ for one year. Avoid repeated freeze/thaw cycles.Stored at 2 to 8 °C for 2 days after thawing. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]
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| 产品图片 |
The purified product was run on 15% SDS-PAGE at reducing conditions. The gel was stained with Coomassie brilliant blue and destained.
Note: The molecular weight of the protein as observed on SDS-PAGE under reducing conditions may differ from its predicted value, due to variations in electrophoretic mobilities.
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