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Recombinant Cyn. monkey ACE2 protein, C-His-Avi (HEK293), Biotin conjugated (bs-47021P-Bio)  
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20ug/2980.00元
100ug/5800.00元
大包装/询价

产品编号 bs-47021P-Bio
英文名称 Recombinant Cyn. monkey ACE2 protein, C-His-Avi (HEK293), Biotin conjugated
中文名称 生物素标记重组食蟹猴血管紧张素转换酶2蛋白
别    名 ACE-2; ACE 2; Angiotensin converting enzyme 2; ACE related carboxypeptidase; ACEH; Angiotensin converting enzyme homolog; Angiotensin converting enzyme like protein; Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2; Angiotensin I converting enzyme 2; DKFZP434A014; EC 3.4.17; angiotensin-converting enzyme 2 precursor; Angiotensin-converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; Metalloprotease MPROT15; Processed angiotensin-converting enzyme 2; A0A2K5X283_MACFA; Recombinant Cyn. monkey ACE2 protein, C-His-Avi (HEK293) / Biotin  
克 隆 号
理论分子量 86.5 kDa
检测分子量 Due to glycosylation, the protein migrates to 87-110 kDa based on Tris-Bis PAGE result.
浓    度 >0.5 mg/ml
纯    度 >95% as determined by Tris-Bis PAGE; >95% as determined by SEC-HPLC
缓 冲 液 Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization.
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]

合成与降解(Synthesis and Degradation) ACE-2的分布范围比较局限,ACE2主要在心脏、肾脏、睾丸中表达显著, 近来人们发现ACE2也分布在胃肠道、脑和肺脏中。 有关学者在研究心脏和肾脏中发现,ACE2在心肌缺血、肾功能衰竭、动脉粥样硬化和糖尿病并发症中,ACE2对血管紧张素产生和降解过程中有一定的生理作用。 特别是对ACE2在具有生理活性的-活性肽产生过程中的作用更值得进一步研究。 ACE2的发现为心血管病和肾脏病研究开辟了新天地,并提供了新的治疗靶
产品图片
The purity of Biotinylated Recombinant Cyno ACE2 Protein is greater than 95% as determined by SEC-HPLC.
Biotinylated Recombinant Cyno ACE2 Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%..
The purity of Biotinylated Cynomolgus ACE2 is greater than 95% as determined by SEC-HPLC.
Biotinylated Cynomolgus ACE2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
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通过国际质量管理体系ISO 9001:2015 GB/T 19001-2016    证书编号: 00124Q34771R2M/1100
通过国际医疗器械-质量管理体系ISO 13485:2016 GB/T 42061-2022    证书编号: CQC24QY10047R0M/1100
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