产品编号 |
bs-47022P-Bio |
英文名称 |
Recombinant human Angiopoietin-like 3 protein, C-His-Avi (HEK293), Biotin conjugated
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中文名称 |
生物素标记重组人Angiopoietin-like 3蛋白 |
别 名 |
AGNPT5; Ang-5; angiopoietin 5; Angiopoietin-5; Angiopoietin-like Protein 3; angiopoietin-related protein 3; ANGPT5angiopoietin-5; ANGPTL3; FHBL2; Recombinant human Angiopoietin-like 3 protein, C-His-Avi (HEK293) / Biotin |
克 隆 号 |
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理论分子量 |
26.6 kDa |
检测分子量 |
Due to glycosylation, the protein migrates to 30-38 kDa based on Tris-Bis PAGE result. |
浓 度 |
>0.5 mg/ml |
纯 度 |
>95% as determined by Tris-Bis PAGE |
缓 冲 液 |
Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.
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产品图片 |
Biotinylated Human Angiopoietin-like 3 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.
Immobilized Biotinylated Human Angiopoietin-like 3,His Tag at 0.5μg/ml (100μl/Well). Dose response curve for Anti-ANGPTL3 Ab. with the EC50 of 11.5ng/ml determined by ELISA.
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