| 产品编号 | bs-47090P-Bio |
| 英文名称 | Recombinant human FGFR4 protein, C-His-Avi (HEK293), Biotin conjugated |
| 中文名称 | 生物素标记重组人FGFR4蛋白 |
| 别 名 | Fibroblast growth factor receptor 4; CD 334; CD334; CD334 antigen; fc13h 10; fc13h10; Fgfr 4; Hydroxyaryl protein kinase; JTK 2; JTK2; MGC20292; Protein tyrosine kinase; TKF; Tyrosine kinase related to fibroblast growth factor receptor; Tyrosylprotein kinase; FGFR4_HUMAN; Recombinant human FGFR4 protein, C-His-Avi (HEK293) / Biotin |
| 克 隆 号 | |
| 理论分子量 | 41.4 kDa |
| 检测分子量 | Due to glycosylation, the protein migrates to 55-72 kDa based on Tris-Bis PAGE result. |
| 浓 度 | ＞0.5 mg/ml |
| 纯 度 | >95% as determined by Tris-Bis PAGE; >95% as determined by SEC-HPLC |
| 缓 冲 液 | Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. [provided by RefSeq, Jul 2008] |
| 产品图片 |
The purity of Biotinylated Recombinant Human FGFR4 Protein is greater than 95% as determined by SEC-HPLC.
Biotinylated Recombinant Human FGFR4 Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
