| 产品编号 | bs-47095P-Bio |
| 英文名称 | Recombinant Cyn. monkey FcRn protein, C-His-Avi (HEK293), Biotin conjugated |
| 中文名称 | 生物素标记重组食蟹猴FcRn蛋白 |
| 别 名 | IgG receptor FcRn large subunit p51; Fc fragment of IgG, receptor transporter, alpha; FCGRT; FcRn alpha chain; FCRN; FCRN, alpha chain; IgG Fc fragment receptor transporter alpha chain; IgG Gc receptor; IgG receptor FcRn large subunit p51 precursor; Immunoglobulin receptor, intestinal, heavy chain; Neonatal Fc receptor; FCGRN_MACFA; Recombinant Cyn. monkey FcRn protein, C-His-Avi (HEK293) / Biotin |
| 克 隆 号 | |
| 理论分子量 | 46.5 kDa |
| 检测分子量 | Due to glycosylation, the protein migrates to 48-50 kDa based on Tris-Bis PAGE result. |
| 浓 度 | ＞0.5 mg/ml |
| 纯 度 | >95% as determined by Tris-Bis PAGE; >95% as determined by SEC-HPLC |
| 缓 冲 液 | Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
FcRN present in the intestinal epithelium of neonatal mice and rats mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn animals to acquire passive immunity. FcRn (also designated FCGRT, Brambell receptor, FcRn å chain, IgG Gc receptor and neonatal Fc-receptor) is comprised of a heavy chain and ∫-2-Microglobulin. FcRn heavy chain shows approximately 35% amino acid identity to an MHC class I molecule. FcRN localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal catabolism. This protection mechanism is a major constituent for ensuring IgG are the longest lived of all plasma proteins. |
| 产品图片 |
The purity of Biotinylated FcRn is greater than 95% as determined by SEC-HPLC.
Biotinylated Recombinant FcRn on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
