产品编号 |
bs-47105P-Bio |
英文名称 |
Recombinant human Glypican 3 protein, C-His-Avi (HEK293), Biotin conjugated
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中文名称 |
生物素标记重组人Glypican 3蛋白 |
别 名 |
GPC3; glypican3; glypican-3; Intestinal protein OCI-5; GTR2-2; MXR7.Intestinal protein OCI-5; GPC3_HUMAN; Recombinant human Glypican 3 protein, C-His-Avi (HEK293) / Biotin |
克 隆 号 |
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理论分子量 |
63.6 kDa |
检测分子量 |
Due to glycosylation, the protein migrates to 70-140 kDa based on Tris-Bis PAGE result. |
浓 度 |
>0.5 mg/ml |
纯 度 |
>95% as determined by Tris-Bis PAGE |
缓 冲 液 |
Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
GPC-3磷脂酰基醇蛋白聚糖-3是一种硫酸类肝素蛋白多糖,GPC-3在不同的组织中具有不同的生物学功能,甚至起着完全不同的作用,可能与肿瘤组织类型、发病机制等密切相关.GPC3在绝大多数HCC(肝细胞癌)患者有表达。
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产品图片 |
Biotinylated Human GPC3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
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