产品编号 |
bs-47169P-Bio |
英文名称 |
Recombinant human Notch 2 protein, C-His-Avi (HEK293), Biotin conjugated
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中文名称 |
生物素标记重组人Notch 2蛋白 |
别 名 |
Neurogenic locus notch homolog protein 2; activated Notch 2; Notch2; hN2; Notch 2 extracellular truncation; Notch 2 intracellular domain; AGS2; hN2; Motch B; N2 antibody neurogenic locus notch homolog protein 2; NOTC2_HUMAN; Notch 2; Notch Drosophila homolog 2; Notch homolog 2; Notch homolog 2 Drosophila; Recombinant human Notch 2 protein, C-His-Avi (HEK293) / Biotin |
克 隆 号 |
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理论分子量 |
57 kDa |
检测分子量 |
Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
浓 度 |
>0.5 mg/ml |
纯 度 |
>95% as determined by Tris-Bis PAGE; >95% as determined by SEC-HPLC |
缓 冲 液 |
Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
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产品图片 |
The purity of Biotinylated Recombinant Human Notch 2 Protein is greater than 95% as determined by SEC-HPLC.
Biotinylated Recombinant Human Notch 2 Protein on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.
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