产品编号 |
bs-47176P-Bio |
英文名称 |
Recombinant human PD-1 protein, C-hFc-Avi (HEK293), Biotin conjugated
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中文名称 |
生物素标记重组人PD-1蛋白 |
别 名 |
Programmed cell death protein 1; CD279; CD279 antigen; hPD 1; hPD-1; hSLE1; PD 1; PD1; PDCD 1; PDCD1; Programmed cell death 1; Protein PD 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2; PDCD1_HUMAN; Recombinant human PD-1 protein, C-hFc-Avi (HEK293) / Biotin |
克 隆 号 |
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理论分子量 |
44.7 kDa |
检测分子量 |
Due to glycosylation, the protein migrates to 65-72 kDa based on Tris-Bis PAGE result. |
浓 度 |
>0.5 mg/ml |
纯 度 |
>95% as determined by Tris-Bis PAGE; >95% as determined by SEC-HPLC |
缓 冲 液 |
Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
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产品图片 |
The purity of Biotinylated Human PD-1 is greater than 95% as determined by SEC-HPLC.
Biotinylated Human PD-1 on Tris-Bis PAGE under reduced . The purity is greater than 95%.
Immobilized Human PD-L1,mFc tag at 0.5μg/ml (100μl/Well). Dose response curve for Biotinylated Human PD-1,hFc tag with the EC50 of 1.1μg/ml determined by ELISA.
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