| 产品编号 |
bs-47197P-Bio |
| 英文名称 |
Recombinant human SIGLEC8 protein, C-His-Avi (HEK293), Biotin conjugated
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| 中文名称 |
生物素标记重组人siglec 8蛋白 |
| 别 名 |
Siglec-8; SAF-2; SAF 2; SAF2; Sialic acid-binding Ig-like lectin 8 Sialic acid binding Ig like lectin 8; Sialoadhesin family member 2; Siglec 8; SIGL8_HUMAN; Recombinant human SIGLEC8 protein, C-His-Avi (HEK293) / Biotin |
| 克 隆 号 |
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| 理论分子量 |
40.7 kDa |
| 检测分子量 |
Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result. |
| 浓 度 |
＞0.5 mg/ml |
| 纯 度 |
>95% as determined by Tris-Bis PAGE; >95% as determined by SEC-HPLC |
| 缓 冲 液 |
Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
| 保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]
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| 产品图片 |
Biotinylated Recombinant human siglec 8 Protein on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.
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