产品编号 |
bs-47202P-Bio |
英文名称 |
Recombinant human TFPI protein, C-His-Avi (HEK293), Biotin conjugated
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中文名称 |
生物素标记重组人TFPI蛋白 |
别 名 |
Tissue factor pathway inhibitor; Tissue factor pathway inhibitor-1; convertin; EPI; Extrinsic pathway inhibitor; LACI; Lipoprotein associated coagulation inhibitor; TFI; TFPI 1; TFPI1; TFPI1_HUMAN; Recombinant human TFPI protein, C-His-Avi (HEK293) / Biotin |
克 隆 号 |
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理论分子量 |
32.1 kDa |
检测分子量 |
Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
浓 度 |
>0.5 mg/ml |
纯 度 |
>95% as determined by Tris-Bis PAGE; >95% as determined by SEC-HPLC |
缓 冲 液 |
Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
TFPI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins.
组织因子途径抑制因子(tissue factor pathway in hibitor, TFPI)是组织因子凝血途径的主要抑制因子, 组织因子途径抑制因子在诸如动脉粥样硬化,血管再狭窄,弥漫性血管内凝血DIC等方面,有一定的研究价值
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产品图片 |
Biotinylated Recombinant Human TFPI Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
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