产品编号 |
bs-47218P-Bio |
英文名称 |
Recombinant human DR5 protein, C-His-Avi (HEK293), Biotin conjugated
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中文名称 |
生物素标记重组人DR4蛋白 |
别 名 |
Tumor necrosis factor receptor superfamily member 10B; TNFRSF10B; sTRAIL Receptor 2; Death receptor 5; CD 262; CD262; CD262 antigen; Death domain containing receptor for TRAIL/Apo2L; Death receptor 5; DR 5; Fas like protein precursor; KILLER; KILLER/DR5; p53 regulated DNA damage inducible cell death receptor (killer); TNF related apoptosis inducing ligand receptor 2; TNF-related apoptosis-inducing ligand receptor 2; TRAIL R2; TRAIL receptor 2; TRAILR2; TRANCER; TRICK2; TRICK2A; TRICK2B; TRICKB; Tumor necrosis factor receptor like protein ZTNFR9; ZTNFR9; TR10B_HUMAN; Recombinant human DR5 protein, C-His-Avi (HEK293) / Biotin |
克 隆 号 |
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理论分子量 |
20 kDa |
检测分子量 |
Due to glycosylation, the protein migrates to 20-25 kDa based on Tris-Bis PAGE result. |
浓 度 |
>0.5 mg/ml |
纯 度 |
>95% as determined by Tris-Bis PAGE; >95% as determined by SEC-HPLC |
缓 冲 液 |
Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
DR5分布比较广泛,包括肝、脾、肺、胸腺和活化T细胞以及一些肿瘤细胞系。APO-2L在诱导转化细胞和肿瘤细胞的调亡中,广泛且迅速,多表达与胞浆。
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产品图片 |
The purity of Biotinylated Human DR5 Protein is greater than 95% as determined by SEC-HPLC.
Biotinylated Recombinant Human DR5 Protein on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.
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