产品编号 |
bs-47225P-Bio |
英文名称 |
Recombinant human VEGFR1 protein, C-His-Avi (HEK293), Biotin conjugated
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中文名称 |
生物素标记重组人VEGFR1蛋白 |
别 名 |
EC 2.7.10; EC 2.7.10.1; Vascular endothelial growth factor receptor 1; VEGF-R1; VEGFR-1; VEGF Receptor 1; FLT-1; vascular permeability factor receptor; vascular endothelial growth factor receptor; vascular endothelial growth factor receptor-1; fms-related tyrosine kinase 1; vascular endothelial growth factor/vascular permeability factor receptor; AI323757; FLT; FLT1; sFlt1; VGFR1_HUMAN; Recombinant human VEGFR1 protein, C-His-Avi (HEK293) / Biotin |
克 隆 号 |
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理论分子量 |
85 kDa |
检测分子量 |
Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result. |
浓 度 |
>0.5 mg/ml |
纯 度 |
>95% as determined by Tris-Bis PAGE; >95% as determined by SEC-HPLC |
缓 冲 液 |
Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes.
VEGFR1/Flt1是一种细胞膜受体激酶,对血管内皮生长因子有高度的亲和性,主要功能是参与血管内皮细胞生长和血管生成的调控。用于各种恶性肿瘤的研究。
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产品图片 |
Biotinylated Recombinant VEGFR1 Protein on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.
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