| 产品编号 |
bs-41554P |
| 英文名称 |
Recombinant HIV1 envelope gp41 protein
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| 中文名称 |
重组艾滋病病毒HIV1 gp41蛋白 |
| 别 名 |
HIV1 gp41; HIV-1 gp41; HIV1gp41; HIVgp41; Transmembrane protein gp41; Glycoprotein 41; Human Immunodeficiency Virus 1; HIV1 ENV (gp160); HIV1 gp160; HIV1gp160; HIV-1 gp160; env; Env polyprotein; Envelope glycoprotein gp160; Glycoprotein 41; gp41; HIV1; HIV1 clade a; HIV1/Clade A; SU; Surface protein; Human Immunodeficiency Virus Type 1 TM; Transmembrane protein; ENV_HV1MV. |
| 克 隆 号 |
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| 理论分子量 |
42 kDa |
| 检测分子量 |
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| 性 状 |
Lyophilized or Liquid |
| 浓 度 |
>1mg/ml |
| 纯 度 |
>95% pure (10% SDS-PAGE, Coomassie blue staining) |
| 缓 冲 液 |
1M urea in PBS with 25mM K2CO3. |
| 保存条件 |
store in 4℃ for short time only, aliquot to avoid
repeated freezing and thawing, store at -20℃. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
人类免疫缺陷病毒Ⅰ型(HIV-1)的包膜糖蛋白gp120、gp41
HIV感染后可刺激机体生产囊膜蛋白（Gp120,Gp41）抗体
病毒呈球形，直径100～120nm，电镜下可见一致密的圆锥状核心，内含病毒RNA分子和酶（逆转录酶、整合酶、蛋白酶），病毒外层囊膜系双层脂质蛋白膜，其中嵌有gp120和gp41，分别组成刺突和跨膜蛋白。
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