| 产品编号 |
V3310 |
| 英文名称 |
Human NT-proBNP Mouse mAb
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| 中文名称 |
人脑纳素前体蛋白单克隆抗体 |
| 别 名 |
Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptide precursor B; Natriuretic peptides B; NPPB; NPPB protein; ANFB_HUMAN; Natriuretic peptides B.proBNP. |
| 克 隆 号 |
10G6 |
| 理论分子量 |
8.5 kDa |
| 检测分子量 |
|
| 性 状 |
Liquid |
| 纯 度 |
>90% as determined by SDS-PAGE |
| 缓 冲 液 |
0.01M PBS(pH7.4). |
| 保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume.
The 32-amino acid polypeptide BNP is secreted attached to a 76–amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing.
应用推荐（Capture-Detection）: V3305-V3306
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