| 产品编号 | bsm-52427R |
| 英文名称 | CAMK2 beta Recombinant Rabbit mAb |
| 中文名称 | 钙/钙调素依赖蛋白激酶CAMK2B重组兔单克隆抗体 |
| 别 名 | CAM2; CAMK2; CAMKB; CaMKIIbeta; MRD54; CaMKII; Ck2b; KCC2B_HUMAN; CAMK2B; CaM kinase II subunit beta; CaMK-II subunit beta; 2.7.11.17; KCC2B_MOUSE; Camk2d; KCC2B_RAT; |
| 抗体来源 | Rabbit |
| 克隆类型 | Recombinant |
| 克 隆 号 | 1H12 |
| 交叉反应 | (predicted: Human,Mouse,Rat) |
| 产品应用 | WB=1:500-1000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 61 kDa |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | Human CaMKII between 200-300 amino acids |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The multifunctional CaMKII beta, or Ca2+/calmodulin-dependent protein kinase II, is a well known effector of calcium- and calmodulin- mediated functions. It is present in many tissues but is most abundant in the brain. CaMKII is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Autophosphorylation plays an important role in the regulation of the kinase activity. CaMKII is required for synaptic plasticity, as in Long Term Potentiation (LTP), a cellular model for learning and memory. SWISS: Q13554 Gene ID: 816 CaMK2b也是丝/苏氨基酸激酶的一种，有称CAMK2G，同属于Ca++/钙调素依赖性蛋白质激酶家族成员。钙／钙调素依赖性蛋白激酶Ⅱb（CaMKⅡb）广泛分布于中枢神经系统内，参与调节神经递质的合成释放、信号转导和突触可塑性的形成以及磷酸化蛋白。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
