| 产品编号 |
D57622 |
| 英文名称 |
Bis(maltolato)oxovanadium(IV)
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| 中文名称 |
双(麦芽醇)氧钒(IV) |
| 别 名 |
BMOV; Bis(maltolato)oxovanadium (IV) |
| 克 隆 号 |
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| CAS |
38213-69-3 |
| 理论分子量 |
317.15 kDa |
| 保存条件 |
Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
BMOV is a potent, reversible, competitive and orally active pan-PTP (protein tyrosine phosphatases)inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent insulin sensitize. BMOV is shown to improve cardiac dysfunctions in diabetic models. BMOV inhibits HCPTPA, PTP1B, HPTPβ and SHP2 with IC50s of 126 nM, 109 nM, 26 nM and 201 nM, respectivelyr[1][2].
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