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Capecitabine (D53623)  
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1mL x 10mM (in DMSO)/215.00元
1g/992.00元
大包装/询价
产品编号 D53623
英文名称 Capecitabine
中文名称 卡培他滨
别    名 RO 09-1978; Xeloda; Capiibine; Capecitibine  
克 隆 号
CAS 154361-50-9
理论分子量 359.35 kDa
保存条件 Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Capecitabine is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.

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