产品中心-北京博奥森生物技术有限公司

产品编号	bsm-63258R
英文名称	EGFR(L858R mutated) Recombinant Rabbit mAb
中文名称	表皮生长因子受体（L858R突变型）重组兔单抗
别名	kinase EGFR; ERBB1; Epidermal growth factor receptor precursor.
抗体来源	Rabbit
克隆类型	Recombinant
克隆号	5C5
交叉反应	Human
产品应用	WB=1:1000-2000,IHC-P=1:100-200,IHC-F=1:100-200,IF=1:50-200,ICC/IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
理论分子量	134 kDa
检测分子量	175
性状	Liquid
免疫原	A synthesized peptide derived from human EGFR (L858R mutated): FG-R-AK
亚型	IgG
纯化方法	affinity purified by Protein A
缓冲液	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
保存条件	Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
产品介绍	Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. SWISS: P00533 Gene ID: 1956