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产品中心-北京博奥森生物技术有限公司
Recombinant Human TNIP1 Protein, N-His (bs-104935P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104935P
英文名称 Recombinant Human TNIP1 Protein, N-His
中文名称
别    名 Naf1; Virion-associated nuclear shuttling protein; VAN; TNFAIP3-interacting protein 1; KIAA0113; HIV-1 Nef-interacting protein; hVAN; A20-binding inhibitor of NF-kappa-B activation 1; Nef-associated factor 1; TNIP1; NAF1; Nip40-1; ABIN-1  
克 隆 号
理论分子量 72.97 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Abin-1 is a 636 amino acid protein that localizes to both the nucleus and the cytoplasm and is shuttled between the two intercellular regions in a CRM1-dependent manner. Expressed ubiquitously with highest expression in spleen and skeletal muscle, Abin-1 interacts with A20 and, via this interaction, interferes with TRAF2-mediated transactivation signals and effectively inhibits TNF-induced NFⅹB expression. Additionally, Abin-1 can be incorporated into HIV-1 virions and, if overexpressed, can inhibit viral replication. Abin-1 may also play an important role in the regulation of nuclear import and export activities. Multiple isoforms of Abin-1 exist due to alternative splicing events.

SWISS:
Q15025

Gene ID:
10318

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