| 产品编号 | bs-105058P |
| 英文名称 | Recombinant Human STC1 Protein, C-His |
| 中文名称 | |
| 别 名 | STC1; Stanniocalcin-1; STC; STC-1 |
| 克 隆 号 | |
| 理论分子量 | 27.98 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq]. SWISS: P52823 Gene ID: 6781 STC1蛋白实在哺乳动物中发现的糖蛋白激素,参与机体的多种生理功能,不但可以通过肾脏和肠道系统来调节钙和磷酸盐的稳态,而且在促进脑神经元的终末分化、防止因大脑局部缺血造成脑神经元的损害、以及骨和肌肉的发育等方面也有重要作用. 近来研究发现,STC-1在人类肿瘤的发生发展中也有着重要的作用.STC-1可作为一种稳定因子促进新生血管的成熟而发挥促肿瘤增殖生长，还可通过自分泌途经与肿瘤细胞表面的趋化因子和整合素相互作用,激活一系列细胞内信号,引起多种蛋白分泌,从而溶解细胞外基质屏障,使肿瘤发生侵 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
