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Recombinant Human COPE Protein, N-His (bs-105214P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-105214P
英文名称 Recombinant Human COPE Protein, N-His
中文名称
别    名 Coatomer subunit epsilon; Epsilon-coat protein; Epsilon-COP; COPE  
克 隆 号
理论分子量 35.3 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

SWISS:
O14579

Gene ID:
11316

共溶体是一种细胞溶质蛋白复合物,与二赖氨酸基序结合,并与高尔基体非网格蛋白包被的囊泡可逆结合,后者进一步介导从内质网经高尔基体向反高尔基体网络的生物合成蛋白转运。共溶体复合体是高尔基体膜出芽所必需的,也是二赖氨酸标记蛋白从高尔基体到内质网逆行转运所必需的。在哺乳动物中,只有与ADP-核糖基化因子(ARFs)相关的膜才能招募共聚体,ARFs是一种小的GTP结合蛋白,这种复合物还影响高尔基体的结构完整性,以及低密度脂蛋白受体的加工、活性和内吞循环。
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