| 产品编号 | bs-105434P |
| 英文名称 | Recombinant Human ARRB2 Protein, N-His |
| 中文名称 | |
| 别 名 | Beta-arrestin-2; Arrestin beta-2; Non-visual arrestin-3; ARRB2; ARB2; ARR2 |
| 克 隆 号 | |
| 理论分子量 | 43.44 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Members of arrestin/beta arrestin protein family are thought to participate in agonist mediated desensitization of G protein coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors SWISS: P32121 Gene ID: 409 β抑制因子-2又称β休止蛋白2,也是是调节CD4+T细胞存活和自身免疫性的关键因子,与促进T淋巴细胞存活和自身免疫发病相关。经研究发现β-arrestin不仅仅能阻断蛋白合成,也能诱导蛋白合成,参与信号传导。 对Arrestins家族的研究-探究β-arrestin在G蛋白偶联受体信号传导通路中的地位和作用,是当今生物学中信号传导研究领域的热门课题. β抑制因子-1又称“胰岛素受体复合体”,近年来国内外科研人员对β-arrestin在II型糖尿病发生的研究机制方面有了新的突破,认为:β-arrestin缺 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |