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产品中心-北京博奥森生物技术有限公司
Recombinant Human FGL2 Protein, N-His (bs-105463P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-105463P
英文名称 Recombinant Human FGL2 Protein, N-His
中文名称
别    名 Fibroleukin; Fibrinogen-like protein 2; pT49; FGL2  
克 隆 号
理论分子量 49.94 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. It may play a role in physiologic functions at mucosal sites. It is constitutively expressed in cytotoxic T-cells. Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes. FGL2 is induced via a mechanism involving IFNG and components of the IFNG signaling pathway, including STAT1 and IRF1.

SWISS:
Q14314

Gene ID:
10875

fgL-2蛋白是新近发现的一种凝血因子,它通过直接激活凝血酶原启动凝血过程。一 系列实验证明,该蛋白在肝细胞坏死中起到重要作用。对乙肝患者肝组织免疫组织化学染色hfg12在重型乙型肝炎患者高表达。 凝血酶原酶(简称fgl2)蛋白属于纤维蛋白原家族的一员,由活化的巨噬细胞表达,具有凝血酶原酶的活力,能催化凝血酶原转化为凝血酶,启动凝血过程.
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