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产品中心-北京博奥森生物技术有限公司
Recombinant Mouse IL18 Protein, N-His (bs-105566P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-105566P
英文名称 Recombinant Mouse IL18 Protein, N-His
中文名称
别    名 Interleukin-18; IL-18; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma; Il18; Igif  
克 隆 号
理论分子量 20.41 kDa
检测分子量
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.

SWISS:
P70380

Gene ID:
Mouse

IL-18是巨噬细胞分泌的一个重要因子,它具有多种免疫功能,能诱导产生IFNγ,无论在病毒感染早期或特异性细胞免疫应答效应阶段都会出现,因此IL-18主要参与免疫应答及炎性细胞浸润的改变。Interleukin-18 又称inteferon-gamma inducing factor(IGIF),在辅助T细胞的应答反应中起重要作用。IL-18和IL-1一起,既参与先天免疫,又是后天免疫的构成因素。
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