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Recombinant Human TNFRSF25 Protein, C-Fc (bs-105615P)  
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20ug/1280.00元
50ug/2580.00元
100ug/4180.00元
大包装/询价
产品编号 bs-105615P
英文名称 Recombinant Human TNFRSF25 Protein, C-Fc
中文名称
别    名 Apoptosis-inducing receptor AIR; Apoptosis-mediating receptor DR3; Apoptosis-mediating receptor TRAMP; Protein WSL-1; LARD; Lymphocyte-associated receptor of death; Tumor necrosis factor receptor superfamily member 25; Apo-3; Protein WSL; APO3; DR3; TNFRSF12; WSL; TNFRSF25; Death receptor 3; DDR3; WSL1  
克 隆 号
理论分子量 47.74 kDa
检测分子量
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008]

SWISS:
Q93038

Gene ID:
8718

死亡受体(death receptor)已经鉴定的有DR3、DR4和DR5,DR3也称为WSL-1,Apo-3受体或TRAMP(TNFR介导的细胞凋亡蛋白质TNF-receptor apoptosis-mediating protein,TRAMP)。 肿瘤坏死因子-α受体(肿瘤坏死因子受体超家TNF-α膜受体族成员)是近年来被鉴定发现的:主要在人的多淋巴细胞组织中。它们同属TNF/NGF受体超家族成员。
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