| 产品编号 | bs-105659P |
| 英文名称 | Recombinant Human ADCY1 Protein, N-His |
| 中文名称 | |
| 别 名 | Ca(2+)/calmodulin-activated adenylyl cyclase; ADCY1; Adenylate cyclase type 1; Adenylyl cyclase 1; ATP pyrophosphate-lyase 1; Adenylate cyclase type I |
| 克 隆 号 | |
| 理论分子量 | 32.84 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The membrane bound adenylyl cyclases (ACs) represent one of the major families of effector enzymes for G protein coupled receptors. Eight human AC isoforms (AC-1 through AC-4) have been identified up to now and genes for at least nine adenylate cyclase (AC-1-AC-9) have been cloned characterized and sequenced. This is a calmodulin-sensitive adenylyl cyclase which may be involved in regulatory processes in the central nervous system. It may play a role in neuronal plasticity, memory acquisition and learning and is expressed predominantly in the brain, retina and adrenal medulla. SWISS: Q08828 Gene ID: 107 腺苷酸环化酶(adenylate cyclase, AC) 是G蛋白偶联受体家族之一，是膜整合蛋白,它的氨基端和羧基端都朝向细胞质。AC在膜的细胞质面有两个催化结构域,还有两个膜整合区,每个膜整合区分别有6个跨膜的α螺旋。哺乳动物中已发现6个腺苷酸环化酶异构体。由于AC能够将ATP转变成cAMP,引起细胞的信号应答,因此,腺苷酸环化酶是G蛋白偶联系统中的效应物。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
