| 产品编号 | bs-105660P |
| 英文名称 | Recombinant Human OPN/SPP1 Protein, N-His-SUMO |
| 中文名称 | |
| 别 名 | Osteopontin; BNSP; Uropontin; OPN; SPP-1; Secreted phosphoprotein 1; Bone sialoprotein 1; Nephropontin; Urinary stone protein; SPP1 |
| 克 隆 号 | |
| 理论分子量 | 18.36 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Osteopontin is the principal phosphorylated glycoprotein of bone and is expressed in a limited number of other tissues including dentine.
Osteopontin is produced by osteoblasts under stimulation by calcitriol and binds tightly to hydroxyapatite. It is also involved in the anchoring of osteoclasts to the mineral of bone matrix via the vitronectin receptor, which has specificity for osteopontin. Osteopontin is overexpressed in a variety of cancers, including lung, breast, colorectal, stomach, ovarian, melanoma and mesothelioma. SWISS: P10451 Gene ID: 6696 骨桥蛋白（osteopontin）又称为早期Ｔ淋巴细胞活化因子Ｉ或分泌型磷蛋白Ｉ,是一种重要的多功能细胞外基质蛋白,在骨组织细胞、巨噬细胞、平滑肌细胞、内皮细胞及上皮细胞等多种细胞上表达,在介导细胞的趋化、聚集、黏附、增殖和迁移,以及骨组织的矿化与重建、免疫调节、信号转导和对感染性疾病的免疫能力等方面有着重要的作用。 ＯＰＮ在细胞免疫中的功能：1.ＯＰＮ对炎性细胞的作用：炎症是炎性细胞(单核巨噬细胞、淋巴细胞、中性粒细胞等)在炎症部位的聚集,适度的炎症对机体有益,如抗感染及促进组织细胞功能恢复等;但过度的 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
