产品编号 | bs-105687P |
英文名称 | Recombinant Human COL10A1, N-His |
中文名称 | |
别 名 | COL10A1; Collagen alpha-1(X) chain |
克 隆 号 | |
理论分子量 | 41.77 kDa |
检测分子量 | |
性 状 | Lyophilized |
纯 度 | >90% as determined by SDS-PAGE. |
缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD). [provided by RefSeq, Jul 2008]. SWISS: Q03692 Gene ID: 1300 Ⅹ型胶原是一种短链的非纤维性胶原,正常存在于软骨化骨中心及骨骺软骨生长板内,仅见于软骨细胞肥大区及钙化区前沿,在关节软骨见于钙化软骨层,由肥大软骨细胞特异表达,只短暂出现,可能参与软骨钙化的调节,是正常和异常骨形成的标志。 有学者认为:Ⅹ型胶原在骨性关节病中可作为软骨细胞表型不可逆转的诊断标志 ,是大量关节软骨细胞发生凋亡,最终导致关节软骨变薄,关节下骨变硬、增厚的主要原因。 |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |