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ANXA2/ANX2 Rabbit pAb (bs-42582R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-42582R
英文名称 ANXA2/ANX2 Rabbit pAb
中文名称 膜粘连蛋白 Ⅱ抗体
别    名 ANXA2_HUMAN; ANXA2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV (PAP-IV); Protein I; p36; ANX2; ANX2L4; CAL1H; LPC2D; ANXA2_MOUSE; ANXA2_RAT;   
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human,Mouse (predicted: Rat)
产品应用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 36 kDa
性    状 Liquid
浓    度 1mg/ml
免 疫 原 Recombinant human ANXA2 protein: 2-339/339 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

SWISS:
P07355

Gene ID:
302

信号传导(Signaling Intermediates) Annexin 2是新近发现的纤维蛋白溶解酶原(PLG)和组织型纤溶蛋白溶解酶原激活物(t-PA)的共受体,是Ca2+介导具有高亲和力的磷脂结合蛋白.其介导血管内外纤维蛋白溶解,对保持机体内环境稳定具有重要作用. 依赖性膜磷脂结合蛋白Annexin II调控异常及有害因子的作用,可导致血栓性疾病和动脉硬化症 钙依赖性膜磷脂结合蛋白膜粘连蛋白2异常高表达所引起纤溶亢进,是白血病等恶性肿瘤出血合并症重要机制之一.钙依赖性磷脂结合蛋白对其干预和调
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