| 产品编号 |
bs-42471P |
| 英文名称 |
Recombinant rabbit IL-4 protein, Tag free
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| 中文名称 |
重组兔子白介素4蛋白 |
| 别 名 |
Interleukin-4; IL-4; IL 4; B cell growth factor 1; B cell IgG differentiation factor; B Cell Stimulatory Factor 1; BCGF 1; BCGF1; Binetrakin; BSF 1; BSF1; HCGF; Hodgkin’s Cell Growth Factor; IA Inducing Factor; IGG1 induction factor; Il4e12; Interleukin 4; Interleukin 4, isoform 1; Interleukin4; Lymphocyte stimulatory factor 1; Macrophage fusion factor; Mast cell growth factor 2; MCGF2; MFF; MGC79402; Pitrakinra; T cell growth factor 2; TCGF2; IL4_HUMAN; B-cell stimulatory factor 1; BSF-1. |
| 克 隆 号 |
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| 理论分子量 |
14.2 kDa |
| 性 状 |
Liquid |
| 纯 度 |
>90% as determined by SDS-PAGE |
| 缓 冲 液 |
20MMTris-HCl (pH=8.0) with 8M Urea, 150mM NaCL |
| 保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
白介素-4仅限于活化T细胞，肥大细胞和噬碱性白细胞。
IL-4对各种淋巴细胞，单核—巨噬细胞，甚至纤维母细胞和上皮细胞都有促生长和分化的作用。
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