| 产品编号 | bs-42600P |
| 英文名称 | Recombinant human CFTR protein, N-His |
| 中文名称 | 重组人囊性纤维化跨膜转运调节因子蛋白 |
| 别 名 | ABC 35; ABC35; ABCC 7; ABCC7; ATP binding cassette sub family C member 7; ATP Binding Cassette Superfamily C Member 7; ATP binding cassette transporter sub family C member 7; cAMP dependent chloride channel; CF; CFTR/MRP; Channel conductance controlling ATPase; Cystic fibrosis transmembrane conductance regulator; Cystic fibrosis transmembrane conductance regulator ATP binding cassette sub family C member 7; ATP-binding cassette sub-family C member 7; cAMP-dependent chloride channel; CFTR; CFTR_HUMAN; Channel conductance-controlling ATPase; Cystic Fibrosis Transmembrane Regulator; Cystic Fibrosis Transmembrane Regulator; dJ760C5.1; MRP 7; MRP7; TNR CFTR; |
| 克 隆 号 | |
| 理论分子量 | 38.7 kDa |
| 性 状 | Liquid |
| 纯 度 | >90% as determined by SDS-PAGE |
| 缓 冲 液 | 20MMTris-HCl (pH=8.0) with 4M Urea, 150mM NaCL |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq, Jul 2008] SWISS: P13569 Gene ID: 1080 CFTR是一种独特的氯离子通道，尽管称为氯离子通道，但在结构上却明显地不同于其他氯离子通道，属于一种ATP结合盒转运体(ATP-binding cassettetransporter, ABC)家族。CFTR主要为氯离子跨上皮运动提供了选择性通道，对于跨上皮的盐类运输、液体流动和离子浓度调节等都具有重要的决定作用。 CFTR分布广泛，许多器官，如肺、肝、胰腺、肠、生殖腺等的细胞膜中都有表达，尽管称为氯离子通道，但还涉及到其他一价阴离子的运输，由于生理条件下氯离子最为重要，故称为氯离子通道，近年来 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
