| 产品编号 | bs-43224P |
| 英文名称 | Recombinant human HLA-G protein, C-His (HEK293) |
| 中文名称 | 重组人类白细胞抗原G蛋白 |
| 别 名 | HLAG_HUMAN; HLA class I histocompatibility antigen, alpha chain G; HLA G antigen; MHC class I antigen G; Soluble HLA class I histocompatibility antigen, alpha chain G; sHLA-G; HLA-6.0; HLAG; MHC-G; |
| 克 隆 号 | |
| 理论分子量 | 34.6 kDa |
| 性 状 | Liquid |
| 纯 度 | >90% as determined by SDS-PAGE |
| 缓 冲 液 | PBS (pH=7.4) |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008] SWISS: P17693 Gene ID: 3135 人类白细胞抗原G/组织相容性白细胞抗原G(Human Leukocyte Antigen-G, HLA-G )是一种非典型的白细胞抗原Ⅰ族组织相溶性抗原。该抗原在正常情况下仅在胎盘的绒毛膜表达。在病理情况下HLA-G只在某些癌细胞表达，在正常组织或良性肿瘤则很少表达.因此, HLA-G是一个具有高度肿瘤特异性的肿瘤标志物。 近年研究认为HLA—G作为免疫耐受分子，在肿瘤免疫逃逸中可能具有重要作用. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
