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Recombinant human GDF-8 protein (Active, CHO) (bs-48108P)  
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产品编号 bs-48108P
英文名称 Recombinant human GDF-8 protein (Active, CHO)
中文名称 重组人生长分化因子8
别    名 GDF 8; GDF-8; GDF8_HUMAN; Growth differentiation factor 8; Growth/Differentiation Factor 8; MSTN; myostatin; OTTHUMP00000163498;  
克 隆 号
理论分子量 12.4 kDa
性    状 Lyophilized
纯    度 ≥ 95% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a 0.22μm-filtered solution containing 0.085% TFA, 30% CAN, 5% Mannitol, pH2.5
保存条件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 23℃ under sterile conditions after reconstitutio
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Myostatin (GDF8)is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 113 amino acid residues and secreted into plasma. Myostatin is a member of the transforming growth factor beta superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology.

SWISS:
O14793

Gene ID:
2660

GDF-8又称MSTN,是转化生长因子超家族,也是近年来发现的一类重要的肌细胞生长调控因子,它通过抑制MyoD家族成员转录活性负向控制肌细胞的生长发育,它的表达量与肌肉重量的变化呈负相关。
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