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Recombinant human Persephin protein (Active, E.coli) (bs-48112P)  
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产品编号 bs-48112P
英文名称 Recombinant human Persephin protein (Active, E.coli)
中文名称 重组人波斯芬
别    名 PSPN_HUMAN; PSP; PSPN;  
克 隆 号
理论分子量 10.3 kDa
性    状 Lyophilized
纯    度 ≥ 95% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a 0.22μm-filtered solution containing 20mM Citric Acid, 5% Mannitol, pH2.5
保存条件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 27℃ under sterile conditions after reconstitutio
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma. [provided by RefSeq, Aug 2016]

SWISS:
O60542

Gene ID:
5623

神经生物学相关蛋白(Neurobiology) PSP是TGF-β家族的一个新亚族,该亚族还有其他三个成员:Neurturin(NTN)、GDNF和Artemin(ART),它们均不同程度地对多巴胺神经元、脊髓前角运动神经元、背根神经节、颈上神经节以及肾等非神经元细胞都具有生长促进作用。研究表明胶质细胞系源性神经营养因子,主要用于PD的研究。
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