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产品中心-北京博奥森生物技术有限公司
Recombinant human IL-15 protein (Active, CHO) (bs-48122P)  
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10ug/750.00元
50ug/2250.00元
500ug/9000.00元
大包装/询价
产品编号 bs-48122P
英文名称 Recombinant human IL-15 protein (Active, CHO)
中文名称 重组人白细胞介素15
别    名 IL15_HUMAN; Interleukin-15; IL 15; Interleukin 15; Interleukin15; MGC9721; IL15; Interleukin-15 (IL-15); Interleukin 15;  
克 隆 号
理论分子量 12.7 kDa
性    状 Lyophilized
纯    度 ≥ 95% as determined by SDS-PAGE.
缓 冲 液 PBS, 5% Mannitol and 0.01% Tween 80, pH7.4
保存条件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 38℃ under sterile conditions after reconstitutio
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 IL15 (114 amino acids) is a cytokine that regulates T and natural killer cell activation and proliferation. It has a predicted molecular mass of approximately 12.5 kDa. Human IL15 shares approximately 97% and 73% amino acid sequence identity with simian and mouse IL15, respectively. Both human and simian IL15 are active on mouse cells. IL15 was initially isolated from the simian kidney epithelial cell line CV1/EBNA. It has also been isolated from mouse and human cell sources. The cytokines IL15 and IL2 share many biological properties and stimulatory activities (T, B, and NK cells). Both IL15 and IL2 stimulate mouse CTLL2 cells. In activated peripheral blood T lymphocytes, IL2 is highly expressed but the expression of IL15 is not detectable. There is no sequence homology between IL15 and IL2, though computer modeling indicates both possess a four alpha helical bundle structure. IL15 competes for binding sites with IL2, as both IL2 and IL15 stimulate the growth of cells through the IL2 receptor. IL15 mRNA is expressed in many cell types and tissues including adherent peripheral blood mononuclear cells, fibroblasts, and epithelial cells, monocytes, placenta, and skeletal muscle.

SWISS:
P40933

Gene ID:
3600

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