| 产品编号 |
bs-46543P |
| 英文名称 |
Recombinant mouse IFNB1/IFN-beta protein, C-Flag (HEK293)
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| 中文名称 |
重组小鼠干扰素β蛋白 |
| 别 名 |
Interferon beta; Ifnb1; IFNB_MOUSE; Ifb; Ifnb; |
| 克 隆 号 |
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| 理论分子量 |
20.3 kDa |
| 性 状 |
Liquid |
| 纯 度 |
> 90 % as determined by SDS-PAGE |
| 缓 冲 液 |
PBS (pH=7.4) |
| 保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015]
β型干扰素(Interferon-β,IFN-β)是主要由成纤维细胞产生的细胞因子,属于单一基因编码产生的蛋白质,可通过干扰病毒RNA或DNA复制而抑制病毒生长,并可显著增强NK细胞杀伤活性,通过促进MHCⅠ类分子表达而增强CTL对病毒感染细胞的识别和杀伤作用.
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