| 产品编号 | bs-42618P |
| 英文名称 | Recombinant human MRP1 protein, N-GST & C-His |
| 中文名称 | 重组人多药耐药相关蛋白1 |
| 别 名 | ABC29; ABCC; DFNA77; GS-X; MRP; MRP1; Abcc1a; Abcc1b; Mdrap; Avcc1a; MRP1_HUMAN; ABCC1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter (LTC4 transporter); 7.6.2.2; |
| 理论分子量 | 38.8kDa |
| 性 状 | Liquid |
| 浓 度 | >1mg/ml |
| 纯 度 | >90% as determined by SDS-PAGE |
| 缓 冲 液 | 50mM Tris-HcL (pH=9.0) with 10mM GSH |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012] SWISS: P33527 Gene ID: 4363 多药耐药相关蛋白1(MRP1)是MRP家族中的一个成员之一，基因的染色体位点是16p13.1，它编码分子量是170-190kDa的MRP1蛋白。 MRP1又称ABCC1主要表达在消化系统中的肝脏、结肠和胰腺组织中，常用于多种肿瘤的多药耐药机制的研究。 |
| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
