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产品中心-北京博奥森生物技术有限公司
Recombinant human GPR49 protein, N-GST & C-His (bs-42626P)  
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20ug/580.00元
100ug/1880.00元
500ug/5680.00元
大包装/询价

产品编号 bs-42626P
英文名称 Recombinant human GPR49 protein, N-GST & C-His
中文名称 重组人G蛋白偶联受体49蛋白
别    名 FEX; GPR49; GPR67; GRP49; HG38; LGR5_HUMAN; LGR5; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; Orphan G-protein coupled receptor FEX;  
理论分子量 36.7kDa
性    状 Liquid
浓    度 >0.5mg/ml
纯    度 >90% as determined by SDS-PAGE
缓 冲 液 50mM Tris-HcL (pH=9.0) with 10mM GSH
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

SWISS:
O75473

Gene ID:
8549

Lgr5基因(Wnt细胞信号系统)是一种G蛋白偶联受体,已经被确定为几种成年组织和癌症中干细胞的一个独特标记。Lgr5最初是在结肠癌细胞中发现的,有报道称:在恶化前的小鼠腺瘤中也有发现,这说明Lgr5很可能也是其他组织成体干细胞和癌症干细胞的标志物。
产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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