| 产品编号 | bs-42615P |
| 英文名称 | Recombinant human Caspase-1 p20 protein, N-His |
| 中文名称 | 重组人天冬氨酸-胱氨酸特异性蛋白酶家族蛋白 |
| 别 名 | ICE; IL1BC; P45; CASP1_HUMAN; CASP1; CASP-1; Interleukin-1 beta convertase (IL-1BC); Interleukin-1 beta-converting enzyme (ICE | IL-1 beta-converting enzyme); 3.4.22.36; IL1BCE; CASP1_MOUSE; CASP1_RAT; |
| 理论分子量 | 23.5kDa |
| 性 状 | Liquid |
| 浓 度 | >1mg/ml |
| 纯 度 | >90% as determined by SDS-PAGE |
| 缓 冲 液 | PBS (pH=7.4) with 4M Urea |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms. [provided by RefSeq]. SWISS: P29466 Gene ID: 834 Caspase-1是半胱氨酸蛋白中的一种酶，参与细胞凋亡的调控。它主要用于各种良、恶性肿瘤的研究。 |
| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
